The Turkish Journal of Pediatrics
2011 , Vol 53 , Num 5
Outcome of Neonates Requiring Assisted Ventilation
Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
Over a two-year period, we studied a total of 100 newborns delivered in our
hospital, needing ventilation. The indications for ventilation, complications,
outcome, and factors influencing outcome were analyzed. Of the 100 babies,
54 were preterm, 44 term and 2 post-term. Overall survival was 58%. The
commonest indication for ventilation was meconium aspiration syndrome in
term babies and hyaline membrane disease in preterms. Babies ventilated for
pneumonia had the best outcome, while the poorest outcome was in sepsis.
Survival increased significantly with increasing birth weight and gestational
age. Downes score, Apgar score and pH at birth did not correlate significantly
with outcome. The maximum peak inspiratory pressure requirement was
significantly higher in the non-survivors. In pneumonia and sepsis, increased
FiO2 requirement significantly impaired survival. The commonest complication
was shock. Incidence of disseminated intravascular coagulation, pulmonary
hemorrhage and pneumothorax was significantly higher in non-survivors;
however, none of these factors was independently predictive of mortality.
Keywords :
neonatal ventilation, outcome, predictors of mortality, indications.