The Turkish Journal of Pediatrics
2010 , Vol 52 , Num 2
Heart Rate Variability in Children with Congenital Sensorineural Deafness
Divisions of 1Pediatric Cardiology, and 2Genetics, Ankara University Faculty of Medicine, Ankara, Turkey
We hypothesized that decreased sympathetic/parasympathetic balance as a
result of the absence of auditory stimuli on the autonomic nervous system
might be an explanation for our previous finding of lower mean heart rate
in congenitally deaf children. To test our hypothesis, we obtained heart rate
variability (HRV) data of 23 children with congenital sensorineural deafness
from 24-hour Holter ECG recordings and compared them to data of 18 healthy
children. HRV was measured by calculating time-domain and frequency-domain
indexes from 24-hour recordings and from 6 hours of recordings obtained
while subjects were sleeping. We additionally compared the HRV values
obtained from children with and without GJB2 gene mutations. We did not
find any significant difference in HRV parameters between deaf children and
healthy children. There were also no significant differences in HRV parameters
between deaf children with and without GJB2 mutations. We conclude that
cardiac autonomic dysfunction does not seem to be present in patients with
congenital sensorineural deafness.
Keywords :
sensorineural deafness, heart rate variability, autonomic nervous system.