The Turkish Journal of Pediatrics 2023 , Vol 65 , Num 3
Short-term outcomes of extremely low birth weight infants in a tertiary neonatal intensive care unit in Türkiye
Sumru Kavurt 1 ,Ahmet Yağmur Baş 2 ,Fatih İşleyen 1 ,Mehtap Durukan Tosun 1 ,Dilek Ulubaş Işık 1 ,Nihal Demirel 2
1 Department of Neonatology, Etlik Zubeyde Hanım Women’s Health Training and Research Hospital, University of Health Sciences, Ankara
2 Department of Neonatology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye
DOI : 10.24953/turkjped.2022.1021 Background. Advances in neonatal care have led to increased survival of extremely preterm infants. Extremely low-birth-weight (ELBW) infants, defined as infants weighing less than 1000 g at birth, constitute a significant portion of neonatal intensive care unit (NICU) patients. The aim of this study is to determine the mortality and short-term morbidities of ELBW infants and assess the risk factors related to mortality.

Methods. The medical records of ELBW neonates hospitalized in the NICU of a tertiary-level hospital between January 2017 and December 2021 were evaluated retrospectively.

Results. 616 ELBW (289 females and 327 males) infants were admitted to the NICU during the study period. Mean birth weight (BW) and gestational age (GA) for the total cohort were 725 ± 134 g (range 420-980 g) and 26.3 ± 2.1 weeks (range 22-31), respectively. The rate of survival to discharge was 54.5% (336/616) [33% for the infants with ≤750 g BW, 76% for the infants with 750-1000 g BW], and 45.2% of survived infants had no major neonatal morbidity at discharge. Independent risk factors for mortality of ELBW infants were asphyxia at birth, birth weight, respiratory distress syndrome, pulmonary hemorrhage, severe intraventricular hemorrhage, and meningitis.

Conclusions. The incidence of mortality and morbidity was very high in ELBW infants, particularly for neonates born weighing less than 750 g in our study. We suggest that preventive and more effective treatment strategies are needed for improved outcomes in ELBW infants. Keywords : extremely low birth weight infant, survival, morbidity

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