The Turkish Journal of Pediatrics 2018 , Vol 60 , Num 1
Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?
Serra Sürmeli-Döven 1 ,Ali Delibaş 1 ,İclal Gürses 2 ,Uğur Raşit Kayacan 3 ,Banu Coşkun-Yılmaz 4 ,Kaan Esen 5 ,Emine Korkmaz 6 ,Fatih Özaltın 6
1 Departments of Pediatric Nephrology, Mersin University Faculty of Medicine, Mersin, Turkey
2 Departments of Pathology, Mersin University Faculty of Medicine, Mersin, Turkey
3 Departments of Pediatrics, Mersin University Faculty of Medicine, Mersin, Turkey
4 Departments of Histology and Embriology, Mersin University Faculty of Medicine, Mersin, Turkey
5 Departments of Radiology, Mersin University Faculty of Medicine, Mersin, Turkey
6 Departments of Pediatric Nephrology and Rheumatology, Nephrogenetics Laboratory, Hacettepe University Faculty of Medicine, Ankara, Turkey
DOI : 10.24953/turkjped.2018.01.012 Sürmeli-Döven S, Delibaş A, Gürses İ, Kayacan UR, Coşkun-Yılmaz B, Esen K, Korkmaz E, Özaltın F. Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not? Turk J Pediatr 2018; 60: 81-85.

A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings. His stool was negative for Shiga toxin producing E. coli (STEC). During follow-up he developed respiratory distress, hypertrophic cardiomyopathy and seizure. His genetic tests for atypical HUS (aHUS) were negative. His clinical and histological findings indicated hemolytic uremic syndrome and immunglobulin A nephropathy (IgAN). The patient responded to steroid treatment and plasma exchange therapy with peritoneal dialysis. We discuss the probable connection between HUS and IgAN. Keywords : Hemolytic uremic syndrome, immunoglobulin A nephropathy, renal failure, glomerulonephritis, childhood

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