The Turkish Journal of Pediatrics 2018 , Vol 60 , Num 1
Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
Gülser Şenses-Dinç 1 ,Uğur Özçelik 2 ,Tuna Çak 3 ,Deniz Doğru-Ersöz 2 ,Esra Çöp 1 ,Ebru Yalçın 2 ,Ebru Çengel-Kültür 3 ,Sevgi Pekcan 4 ,Nural Kiper 2 ,Fatih Ünal 3
1 Clinics of Child and Adolescent Psychiatry, Ministry of Health Ankara Children’s Health and Pediatric Hematology- Oncology Training and Research Hospital, , Ankara, Turkey
2 Departments of Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey
3 Departments of Child and Adolescent Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey
4 Departments of Pediatric Pulmonology, Selcuk University Meram Faculty of Medicine, Konya, Turkey
DOI : 10.24953/turkjped.2018.01.005 Şenses-Dinç G, Özçelik U, Çak T, Doğru-Ersöz D, Çöp E, Yalçın E, Çengel-Kültür E, Pekcan S, Kiper N, Ünal F. Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis. Turk J Pediatr 2018; 60: 32-40.

The aim of this study was to investigate psychiatric disorders, depression and anxiety levels, and quality of life in children and adolescents with cystic fibrosis (CF), and to compare them with those of children with non-cystic fibrosis (non-CF) bronchiectasis and healthy controls. A total of 103 children and adolescents aged 7-16 years (35 CF, 28 non-CF bronchiectasis, 40 healthy) were evaluated using The Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS), The Child Depression Inventory (CDI), The State-Trait Anxiety Inventories for Children (STAI-C) and the Pediatric Quality of Life Inventory (PedsQL)-C. The three groups were not statistically different with respect to age, sex, and familial sociodemographic variables. 80% of the children and adolescents in the CF group were diagnosed with a psychiatric disorder, which was significantly more compared to those of the two other groups. The CF group had significantly greater rates of depressive and oppositional defiant disorder and the non-bronchiectasis group had a significantly greater rate of anxiety disorder than the control group. The depression and anxiety symptom levels were significantly greater and the quality of life levels significantly lower in both the CF and non-CF bronchiectasis groups than the healthy controls. In the CF group, the presence of any associated psychiatric disorder led to significantly lower total and psychosocial quality of life scores. In conclusion, CF is associated with poorer QOL in childhood. In order to improve quality of life in CF, the psychiatric conditions of children and adolescents should also be evaluated and their follow-up and treatment should involve a multidisciplinary team approach. Keywords : cystic fibrosis, children, psychopathology, quality of life

Copyright © 2016 turkishjournalpediatrics.org