The Turkish Journal of Pediatrics 2015 , Vol 57 , Num 1
Idiopathic Central Diabetes Insipidus Presenting in a Very Low Birth Weight Infant Successfully Managed with Lyophilized Sublingual Desmopressin
Departments of Neonatology, 1Adana Gynecology and Obstetric and Children’s Hospital, 2Başkent University Faculty of Medicine, and 4Adana Acıbadem Hospital, and 3Department of Pediatrics, Adana Numune Training and Research Hospital, Adana, Turkey. E-mail: Neonatal central diabetes insipidus (DI) is an extremely rare disorder that can cause severe morbidity and mortality. We have reported a very low birth weight infant with idiopathic central DI presenting in the first month of life who was successfully treated with sublingual desmopressin therapy. In this report, we emphasize that central DI should be kept in mind in an infant with unexplained hypernatremia and polyuria. Timely diagnosis and treatment with lyophilized desmopressin may prevent severe morbidity and mortality. Keywords : central diabetes insipidus, premature infant, desmopressin therapy, hypernatremia, polyuria.
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