The Turkish Journal of Pediatrics 2014 , Vol 56 , Num 2
The Application of Nasal Synchronized Intermittent Mandatory Ventilation in Primary Apnea of Prematurity
Department of Pediatrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, China. E-mail: We aimed to evaluate the efficacy of nasal synchronized intermittent mandatory ventilation (nSIMV) in preterm infants with primary apnea of prematurity (AOP). Forty-four preterm infants with AOP were divided into the nSIMV group or nasal continuous positive airway pressure (nCPAP) group. Clinical symptoms, signs and blood gas results following nSIMV or nCPAP were compared between the two groups. Infants receiving nSIMV had a greater reduction in apneic spells and a greater decrease in bradycardia than those receiving nCPAP. Compared with the nCPAP group, the nSIMV group had a lower incidence of respiratory support failure (9.1% vs. 27.3%; p<0.05), a lower incidence of hypercarbia (4.5% vs. 18.2%; p<0.05) and a lower incidence of gastrointestinal complications (4.5% vs. 13.6%; p<0.05). This study showed that nSIMV was more effective in respiratory support in preterm infants with AOP. Keywords : primary apnea of prematurity, nasal synchronized intermittent mandatory ventilation, nasal continuous positive airway pressure ventilation.
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