The Turkish Journal of Pediatrics 2013 , Vol 55 , Num 4
Posterior Reversible Encephalopathy Syndrome due to Pulse Methylprednisolone Therapy in a Child
Division of 1Pediatric Neurology, 2Pediatric Intensive Care Unit, and 3Pediatric Immunology, Department of Pediatrics, Çukurova University Faculty of Medicine, Adana, Turkey. E-mail: Posterior reversible leukoencephalopathy syndrome (PRES) is a recently described disorder with typical radiological findings of bilateral grey and white matter abnormalities in the posterior regions of the cerebral hemispheres. It has been described in children in association with some medications, renal disease, autoimmune disease, transplantation, and sepsis. In this report, we discuss an eight-year-old boy with PRES during pulse methylprednisolone therapy. In conclusion, PRES is a neurological complication of pulse methylprednisolone therapy, which responds favorably to prompt therapy withdrawal and blood pressure control. Keywords : posterior reversible leukoencephalopathy syndrome, pulse methylprednisolone therapy, children.
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