The Turkish Journal of Pediatrics
2010 , Vol 52 , Num 1
Generalized aggressive periodontitis in a child with 92, XXYY / 46,XY mosaicism: report of a second case
1Department of Periodontology, Kırıkkale University Faculty of Dentistry, Kırıkkale, and 2Departman of Genetics, Selçuk
University Faculty of Medicine, Konya, Turkey
The present case report describes the oral features of tetraploid/diploid
mosaicism. An 11-year-old boy with severe periodontal destruction is presented
in this report. He was examined clinically, radiologically, immunologically,
and genetically. Significant edema of the gingiva, severe sulcular bleeding on
probing and mobility of many teeth were detected on intraoral examination.
There was severe generalized maxillary and mandibular bone loss as
determined by radiological examination. He was diagnosed as generalized
aggressive periodontitis. The cytogenetic examination revealed 92,XXYY
(4%) / 46,XY (96%) karyotype indicating tetraploid/diploid mosaicism. Nonsurgical
periodontal therapy was applied and he is currently under a routine
follow-up period. In this report, the oral characteristics of tetraploid/diploid
mosaicism are described. Dental practitioners should see these patients in
some distinct periods, because tetraploid/diploid mosaicism subjects may
have aggressive periodontitis.
Keywords :
mosaicism, tetraploid/diploid, therapy, aggressive periodontitis.