The Turkish Journal of Pediatrics 2022 , Vol 64 , Num 6
Familial clustering of nasopharyngeal carcinoma in the family of an adolescent with nasopharyngeal carcinoma
Buket Kara 1 ,Kübra Ertan 2 ,Mürsel Düzova 3 ,Ahmet Okay Çağlayan 4 ,Yavuz Köksal 1
1 Division of Pediatric Hematology and Oncology, Selcuk University Faculty of Medicine, Konya
2 Departments of Pediatrics, Selcuk University Faculty of Medicine, Konya
3 Radiation Oncology, Selcuk University Faculty of Medicine, Konya
4 Department of Medical Genetics, Dokuz Eylul University Faculty of Medicine, İzmir, Türkiye
DOI : 10.24953/turkjped.2022.62 Background. Nasopharyngeal carcinoma (NPC) is one of the rare malignant diseases of childhood, of which only 1% occurs in children. In recent years, genetic factors have attracted attention in NPC. A very limited data have been reported about clustering within families.

Case. Herein, the familial clustering of nasopharyngeal carcinoma in the family of an adolescent with nasopharyngeal carcinoma is presented.

Conclusions. There is familial clustering in nasopharyngeal carcinoma (NPC), but our knowledge on this subject is limited, especially in children or adolescent populations. Therefore, we should be more careful in NPC in childhood, especially in first-degree relatives. Keywords : adolescent, nasopharyngeal carcinoma, familial nasopharyngeal carcinoma

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