The Turkish Journal of Pediatrics 2018 , Vol 60 , Num 4
Doxylamine succinate overdose: Slurred speech and visual hallucination
Okşan Derinöz-Güleryüz 1
1 Department of Pediatric Emergency, Gazi University Faculty of Medicine, Ankara, Turkey DOI : 10.24953/turkjped.2018.04.015 Derinöz-Güleryüz O. Doxylamine succinate overdose: Slurred speech and visual hallucination. Turk J Pediatr 2018; 60: 439-442.

Doxylamine succinate is a commonly used antihistamine for respiratory allergies including allergic rhinitis as well as for the management of insomnia. As it is available over-the-counter like other nonprescription antihistamines and sleep aids, there is a risk of overdose. It is believed that doxylamine succinate has both peripheral and central activity with its anticholinergic properties. Delirium, seizures, and coma are among the central adverse effects that are rare. This case was presented since it is the first case in the literature who developed slurred speech and visual hallucination after high dose doxylamine succinate use and received antidotal therapy for anticholinergic side effects. Keywords : doxylamine, overdose, slurred speech, visual hallucination

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