The Turkish Journal of Pediatrics 2012 , Vol 54 , Num 6
Autoimmunity in Inflammatory Bowel Disease: A Case of Ulcerative Colitis with Diabetes Mellitus, Autoimmune Hepatitis and Autoimmune Hypothyroidism
1Pediatrics Center of Excellence, Children’s Medical Center, 2Research Center for Immunodeficiencies, and 3Molecular Immunology Research Center, and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. E-mail: Ulcerative colitis (UC) is a form of inflammatory bowel disease, which occasionally can be associated with autoimmune disorders. Herein, a twoyear- old male infant with UC under sulfasalazine therapy is presented, who consequently developed type I diabetes mellitus, autoimmune hepatitis and autoimmune hypothyroidism. Although presence of concurrent autoimmune diseases with UC is a rare condition, it could highlight the role of immunerelated mechanisms as a pathogenesis of disease. Keywords : autoimmune diseases, autoimmune hepatitis, diabetes mellitus, ulcerative colitis.
Copyright © 2016