The Turkish Journal of Pediatrics 2008 , Vol 50 , Num 1
Foamy histiocytes in a patient with visceral leishmaniasis after treatment with liposomal amphotericin B
1Units of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Turkey
2Units of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey
3Units of Pediatric Gastroenterology, Hepatology and Nutrition, Hacettepe University Faculty of Medicine, Ankara, Turkey
Tavil B, Seçmeer G, Özen H, Cengiz AB, Ünal Ş, Gürgey A. Foamy histiocytes in a patient with visceral leishmaniasis after treatment with liposomal amphotericin B. Turk J Pediatr 2008; 50: 67-69.

A seven-year-old patient was admitted to our hospital with the complaints of fever, malaise, and abdominal distention. In the bone marrow aspiration smears, leishmania amastigotes were observed. The patient was diagnosed as having visceral leishmaniasis (VL) and treated with liposomal amphotericin B (L-AMB). The authors report their observation of foamy histiocytes seen in the bone marrow aspiration smears of the patient with VL after L-AMB treatment. This effect of L-AMB needs to be recognized, since L-AMB may represent a further condition in addition to the other diseases that are associated with foamy histiocytes in the bone marrow. Keywords : foamy histiocytes, visceral leishmaniasis, liposomal amphotericin B

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