The Turkish Journal of Pediatrics 2007 , Vol 49 , Num 2
Hepatitis A super infection as a cause of liver failure in a child with Wilson's disease
1Departments of Pediatrics, Başkent University Faculty of Medicine, Ankara, Turkey
2 Departments of Pathology, Başkent University Faculty of Medicine, Ankara, Turkey
Özçay F, Canan O, Akcan B, Bilezikçi B. Hepatitis A super infection as a cause of liver failure in a child with Wilson's disease. Turk J Pediatr 2007; 49: 199-202.

Infection with hepatitis A virus can cause severe or even fatal illness in patients with chronic liver disease. Here we describe a seven-year-old girl who presented as acute liver failure and was diagnosed with Wilson's disease and later with coexistent hepatitis A infection. Wilson's disease was demonstrated on the basis of low ceruloplasmin, high urinary copper excretion, histological evidence of cirrhosis, and high biochemical estimation of liver copper concentration. Hepatitis A was diagnosed serologically. Our case suggests that acute hepatitis A may play a part in the acute decompensation seen in some cases of unrecognized Wilson's disease. We also emphasize the importance of prevention measures of hepatitis A infection in patients with chronic liver disease. Keywords : Acute liver failure, hepatitis A infection, Wilson's disease

Copyright © 2016 turkishjournalpediatrics.org