2Division of Pediatric Neurology Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey Akıncı G, Polat M, Tosun A, Serdaroğlu G, Gokben S, Tekgül H. Miller Fisher syndrome: a case with pattern of pure sensory polyneuropathy concomitant with anti-GQ1b antibody. Turk J Pediatr 2007; 49: 109-112.
Miller Fisher syndrome is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia. Anti-GQ1b antibodies are useful markers for the differential diagnosis of Miller Fisher syndrome. We describe the case of a seven-year-old male who presented with a four-day history of diplopia and ophthalmoplegia following a febrile flu-like illness with sore throat. On examination he was found to have ataxia, areflexia and ophthalmoplegia, and a diagnosis of Miller Fisher syndrome was made after the exclusion of other conditions and concomitant with electrophysiological findings on electromyography. Although this disorder has a rare incidence, it should still be considered in the differential diagnosis in our country.
Keywords : ophthalmoplegia, ataxia, areflexia, anti-GQ1b IgG antibody, electromyography