The Turkish Journal of Pediatrics 2018 , Vol 60 , Num 1
Pediatric primary anaplastic ganglioglioma with malignant neuronal component
Meriç Kaymak-Cihan 1 ,Eda Erdiş 2 ,Süheyla Bozkurt 3 ,Elif Ünver-Korğalı 4
1 Departments of Pediatric Hematology and Oncology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
2 Departments of Radiation Oncology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
3 Department of Pathology, Marmara University Faculty of Medicine, İstanbul, Turkey
4 Departments of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
DOI : 10.24953/turkjped.2018.01.017 Kaymak-Cihan M, Erdiş E, Bozkurt S, Ünver-Korğalı E. Pediatric primary anaplastic ganglioglioma with malignant neuronal component. Turk J Pediatr 2018; 60: 102-106.

Gangliogliomas (GGs) represent approximately 0.4%-1.0% of all brain tumors. Anaplastic gangliogliomas (AGGs) form 5-10% of all GGs. They are a mixed neuronal-glial tumor of central nervous system and composed by two cell lines; neuronal (ganglionic) and glial cells. Anaplastic component of AGGs is usually glial cells. Malignant neuronal component is a rare condition. Here we report an 8-year-old male patient who was diagnosed with primary AGG with malignant neuronal component and was treated with surgery, adjuvant radiotherapy and chemotherapy. Keywords : anaplastic ganglioglioma, malignant neuronal component, pediatrics

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