The Turkish Journal of Pediatrics 2004 , Vol 46 , Num 3
Acute arterial thrombotic purpura complicating varicella and the role of hyperbaric oxygen as an adjunctive therapy

Department of Pediatrics, Social Security Foundation, Bakırköy Maternity and Children's Training Hospital

Department of Submarine Medicine, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul, Turkey

Abstract

Şiraneci R, Hatipoğlu N, Hatipoğlu H, Dündar K, Baygın L, Yıldız C, Türel Ö. Acute arterial thrombotic purpura complicating varicella and the role of hyperbaric oxygen as an adjunctive therapy. Turk J Pediatr 2004; 46: 256-258.

Chickenpox is a common infectious disease of the pediatric age group with rare complications such as hemorrhagic varicella and arterial thrombotic purpura. Medical support is the mainstay of treatment in such cases but for the rescue of necrotic tissues, hyperbaric oxygen (HBO) therapy should be applied in addition to anticoagulant intervention. We report an infant with acute arterial thrombotic purpura which developed after varicella eruption and who made full recovery with the help of HBO as an adjunctive treatment modality. Fresh frozen plasma and low molecular weight heparin were given for prolonged prothrombin time and thromboemboli on the 2nd-4th digits of his right foot. Protein C, protein S and factor V levels were found to be normal in our patient. Necrotic lesions on the toes regressed with repeated HBO treatment and amputation was not needed. Keywords : chickenpox thrombotic purpura hyperbaric oxygen therapy

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