The Turkish Journal of Pediatrics 2014 , Vol 56 , Num 4
Development of Fatty Liver in Children with Non-Hodgkin Lymphoma
1Division of Pediatric Hematology and Oncology, 3Department of Pediatrics and 4Department of Radiology, Selcuk University Faculty of Medicine, Konya, 2Department of Radiology, Medipol University Faculty of Medicine, İstanbul, Turkey
E-mail: yavuzkoksal@yahoo.com
The aim of this study is to investigate the development of hepatosteatosis in children with non-Hodgkin lymphoma. Twenty-eight patients were evaluated retrospectively for hepatosteatosis by computed tomography. Mild, moderate and severe hepatosteatosis were defined as the difference between the average liver attenuation and the average spleen attenuation, equaling (– 10) - (– 19); (– 20) - (– 29); and ≥30 HU, respectively. “Vaguely” and “obvious” hepatosteatosis were defined as none or mild hepatosteatosis, and moderate and severe hepatosteatosis, respectively. In T-cell lymphoma, obvious hepatosteatosis was determined in 1 of 12 patients (8.3%) at the first evaluation, 8 of 12 patients (66.7%) at the second evaluation and 4 of 12 patients (33.3%) at the third evaluation. In B-cell lymphoma, obvious hepatosteatosis was determined in none of 16 patients at the first evaluation, 2 of 16 patients (12%) at the second evaluation and none of the patients at the third evaluation. In the second evaluation, severe high serum total cholesterol and triglyceride levels were determined in 4 of 5 patients. We observed higher fatty liver ratios, and high triglyceride and cholesterol levels, although the data were obtained from a small number of patients. Keywords : children, fatty liver, lymphoma, non-Hodgkin.
Copyright © 2016 turkishjournalpediatrics.org